Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 0.49 |
| ▸ | MMP9 | P14780 | 17/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876861 | 0.90 | MMP2 (0.55) | MMP2MMP9MMP1MMP14ADAM17 | |
| SCHEMBL877006 | 0.88 | MMP2 (0.51) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL876385 | 0.87 | MMP2 (0.59) | MMP2MMP9MMP1MMP14MMP3 | |
| SCHEMBL877131 | 0.84 | MMP2 (0.64) | MMP2MMP9MMP1MMP14MMP3 | |
| SCHEMBL877176 | 0.79 | MMP2 (0.48) | MMP2MMP9MMP1MMP14MMP3 | |
| SCHEMBL874167 | 0.77 | LPAR1 (0.49) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL877810 | 0.77 | GPR139 (0.50) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL877694 | 0.76 | MMP2 (0.47) | MMP2MMP9MMP1MMP14MMP3 | |
| SCHEMBL874425 | 0.75 | MMP2 (0.48) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL2561591 | 0.70 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |