Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.48 |
| ▸ | MMP9 | P14780 | 15/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876986 | 0.86 | CA1 (0.44) | MMP2MMP9MMP3MMP13CA1 | |
| SCHEMBL874167 | 0.86 | LPAR1 (0.49) | MMP2MMP9MMP3MMP13CA1 | |
| SCHEMBL877592 | 0.86 | MMP2 (0.41) | MMP2MMP9MMP3MMP13CA1 | |
| SCHEMBL877694 | 0.85 | MMP2 (0.47) | MMP2MMP9MMP3MMP13CA1 | |
| SCHEMBL876861 | 0.82 | MMP2 (0.55) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL873568 | 0.78 | GPR139 (0.44) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL873973 | 0.78 | KDM4E (0.42) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL877131 | 0.77 | MMP2 (0.64) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL877277 | 0.75 | MMP2 (0.49) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL877006 | 0.74 | MMP2 (0.51) | MMP2MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |