Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 11/20 | 0.41 |
| ▸ | MMP9 | P14780 | 11/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877694 | 0.93 | MMP2 (0.47) | LPAR1LPAR3MMP2MMP9ALDH1A1 | |
| SCHEMBL876986 | 0.88 | CA1 (0.44) | MMP2MMP9MMP3MMP13CA1 | |
| SCHEMBL874425 | 0.86 | MMP2 (0.48) | MMP2MMP9HTTMMP3MMP13 | |
| SCHEMBL876385 | 0.81 | MMP2 (0.59) | MMP2MMP9TDP1LMNASMN1; SMN2 | |
| SCHEMBL6727028 | 0.81 | DUT (0.49) | LPAR1LPAR3MMP2MMP9HTT | |
| SCHEMBL877131 | 0.79 | MMP2 (0.64) | MMP2MMP9TDP1ALDH1A1MMP3 | |
| SCHEMBL876861 | 0.78 | MMP2 (0.55) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL877277 | 0.77 | MMP2 (0.49) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL877006 | 0.76 | MMP2 (0.51) | MMP2MMP9ALDH1A1MMP3MMP13 | |
| SCHEMBL877592 | 0.75 | MMP2 (0.41) | MMP2MMP9HTTALDH1A1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |