Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770643 | 0.90 | ITGB3 (0.50) | KMT2ASMN1; SMN2ALOX15HTTITGB3 | |
| SCHEMBL8770319 | 0.84 | KMT2A (0.43) | KMT2AALDH1A1SMN1; SMN2ALOX15HTT | |
| SCHEMBL8770307 | 0.79 | ITGB3 (0.60) | KMT2AALDH1A1SMN1; SMN2ALOX15HTT | |
| SCHEMBL8770635 | 0.78 | ITGB3 (0.44) | KMT2AALDH1A1SMN1; SMN2ALOX15HTT | |
| SCHEMBL8770179 | 0.69 | ITGB3 (0.74) | KMT2AITGB3ITGA2B | |
| SCHEMBL3254358 | 0.68 | L3MBTL1 (0.43) | KMT2AALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL8770650 | 0.67 | ITGB3 (0.55) | KMT2AITGB3ITGA2B | |
| SCHEMBL8770310 | 0.67 | SMN1; SMN2 (0.60) | KMT2AALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL7299583 | 0.65 | HPGD (0.46) | KMT2AALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL8770267 | 0.64 | SLC6A2 (0.46) | ALDH1A1SMYD3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |