Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948356 | 0.80 | NPSR1 (0.32) | ALDH1A1MAPK1MAPTNPSR1LMNA | |
| SCHEMBL8770689 | 0.79 | ALDH1A1 (0.32) | ALDH1A1MAPTNPSR1HSD17B10L3MBTL1 | |
| SCHEMBL8464103 | 0.77 | IKBKB (0.37) | IKBKBALDH1A1HTTMAPK1NPC1 | |
| SCHEMBL8770789 | 0.76 | ALDH1A1 (0.36) | IKBKBALDH1A1HTTMAPK1NPC1 | |
| SCHEMBL8465883 | 0.75 | IKBKB (0.39) | IKBKBALDH1A1HTTNPC1MAPT | |
| SCHEMBL8770747 | 0.74 | L3MBTL1 (0.41) | TDP1MAPTL3MBTL1 | |
| SCHEMBL27968702 | 0.73 | IKBKB (0.42) | IKBKBALDH1A1HTTMAPK1MAPT | |
| SCHEMBL8948445 | 0.72 | ALDH1A1 (0.31) | ALDH1A1HTTMAPTHSD17B10 | |
| SCHEMBL8461473 | 0.72 | HCRTR1 (0.31) | — | |
| SCHEMBL8488369 | 0.72 | ALDH1A1 (0.44) | IKBKBALDH1A1HTTMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796246-A1 | 3-BENZOYLPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5565413-A | Substituted pyridyl phenyl ketone herbicides | ZENECA LIMITED (GB) | 1996-10-15 | — | — | US | disclosed |
| WO-1996017829-A2 | 3-BENZOYLPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1996-06-13 | — | — | WO | disclosed |