Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770689 | 0.90 | ALDH1A1 (0.32) | NPSR1L3MBTL1HPGDALDH1A1MAPT | |
| SCHEMBL8770613 | 0.80 | IKBKB (0.37) | NPSR1L3MBTL1MAPK1ALDH1A1MAPT | |
| SCHEMBL8465883 | 0.75 | IKBKB (0.39) | L3MBTL1MEN1HPGDTSHRKMT2A | |
| SCHEMBL8464103 | 0.74 | IKBKB (0.37) | NPSR1L3MBTL1MEN1MAPK1KMT2A | |
| SCHEMBL8770747 | 0.74 | L3MBTL1 (0.41) | L3MBTL1MAPTCYP2C9 | |
| SCHEMBL8948445 | 0.72 | ALDH1A1 (0.31) | MEN1HPGDKMT2AALDH1A1MAPT | |
| SCHEMBL8461473 | 0.72 | HCRTR1 (0.31) | — | |
| SCHEMBL8461471 | 0.69 | HCRTR2 (0.31) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL3867685 | 0.68 | ALDH1A1 (0.35) | NPSR1HPGDTSHRALDH1A1MAPT | |
| SCHEMBL8465758 | 0.68 | KMT2A (0.34) | MEN1TSHRKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565413-A | Substituted pyridyl phenyl ketone herbicides | ZENECA LIMITED (GB) | 1996-10-15 | — | — | US | disclosed |