Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948356 | 0.74 | NPSR1 (0.32) | L3MBTL1MAPTCYP2C9 | |
| SCHEMBL8770613 | 0.74 | IKBKB (0.37) | L3MBTL1MAPTTDP1 | |
| SCHEMBL8770689 | 0.73 | ALDH1A1 (0.32) | L3MBTL1MAPT | |
| SCHEMBL8465883 | 0.72 | IKBKB (0.39) | L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8464103 | 0.68 | IKBKB (0.37) | L3MBTL1MAPT | |
| SCHEMBL8948445 | 0.67 | ALDH1A1 (0.31) | MAPT | |
| SCHEMBL8881471 | 0.66 | MRGPRX4 (0.49) | L3MBTL1MAPTSMN1; SMN2PTGER1MRGPRX4 | |
| SCHEMBL8770756 | 0.66 | L3MBTL1 (0.35) | L3MBTL1MAPTPPIACNR1CNR2 | |
| SCHEMBL8461473 | 0.66 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL28709109 | 0.66 | MAPT (0.69) | L3MBTL1MAPTCYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796246-A1 | 3-BENZOYLPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5565413-A | Substituted pyridyl phenyl ketone herbicides | ZENECA LIMITED (GB) | 1996-10-15 | — | — | US | disclosed |