Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770883 | 0.87 | L3MBTL1 (0.73) | L3MBTL1AOC3CHRM2CHRM1CHRM3 | |
| SCHEMBL4115797 | 0.86 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL8770968 | 0.85 | SMN1; SMN2 (0.50) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL13724830 | 0.84 | L3MBTL1 (0.55) | L3MBTL1AOC3ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7189616 | 0.83 | L3MBTL1 (0.53) | L3MBTL1AOC3ALDH1A1TSHRMAPK1 | |
| SCHEMBL27553225 | 0.83 | L3MBTL1 (0.77) | L3MBTL1AOC3CHRM2CHRM1CHRM3 | |
| SCHEMBL27553226 | 0.83 | L3MBTL1 (0.77) | L3MBTL1AOC3CHRM2CHRM1CHRM3 | |
| SCHEMBL1369571 | 0.82 | L3MBTL1 (0.52) | L3MBTL1AOC3ALDH1A1TSHRMAPK1 | |
| SCHEMBL24643324 | 0.82 | ALOX15 (0.57) | L3MBTL1AOC3ALDH1A1ALOX15 | |
| SCHEMBL4811149 | 0.82 | ALOX15 (0.57) | L3MBTL1AOC3ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |