Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770924 | 0.85 | CES2 (0.39) | CES2CES1 | |
| SCHEMBL17857566 | 0.84 | HDAC4 (0.40) | CES2CES1HDAC4HDAC7HDAC5 | |
| SCHEMBL8770903 | 0.84 | L3MBTL1 (0.49) | CES2CES1L3MBTL1HDAC4HDAC7 | |
| SCHEMBL8770896 | 0.83 | L3MBTL1 (0.43) | L3MBTL1CTSSCTSKMAPT | |
| SCHEMBL8770902 | 0.83 | L3MBTL1 (0.43) | L3MBTL1 | |
| SCHEMBL8770937 | 0.82 | AOC3 (0.42) | CTSSCTSKMAPT | |
| SCHEMBL8770863 | 0.82 | L3MBTL1 (0.66) | CES2CES1L3MBTL1 | |
| SCHEMBL28857505 | 0.82 | RIPK1 (0.51) | L3MBTL1CTSSCTSKMAPT | |
| SCHEMBL5654433 | 0.82 | RIPK1 (0.51) | L3MBTL1CTSSCTSKMAPT | |
| SCHEMBL8770874 | 0.81 | APP (0.42) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |