Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770893 | 0.85 | APP (0.39) | CYP2D6 | |
| SCHEMBL13482971 | 0.84 | ADRB3 (0.53) | L3MBTL1ADRB3ADRB1ADRB2GLA | |
| SCHEMBL30088535 | 0.84 | ADRB3 (0.53) | L3MBTL1ADRB3ADRB1ADRB2GLA | |
| SCHEMBL8770895 | 0.84 | ADRB3 (0.53) | L3MBTL1ADRB3ADRB1ADRB2GLA | |
| SCHEMBL8770896 | 0.83 | L3MBTL1 (0.43) | L3MBTL1 | |
| SCHEMBL8770988 | 0.83 | CES2 (0.43) | L3MBTL1 | |
| SCHEMBL8770867 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL21656114 | 0.82 | GABBR2 (0.41) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8770922 | 0.82 | AOC3 (0.42) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8770863 | 0.82 | L3MBTL1 (0.66) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |