Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770906 | 0.88 | ADRB2 (0.51) | CYP2D6NFKB1ADRB2ADRB1HIF1A | |
| SCHEMBL8770882 | 0.84 | MEN1 (0.44) | MEN1KMT2AKCNH2CYP2D6NFKB1 | |
| SCHEMBL8771031 | 0.81 | CASP1 (0.48) | MEN1KMT2ACYP2D6NFKB1CYP1A2 | |
| SCHEMBL256639 | 0.80 | DRD2 (0.46) | CYP2D6NFKB1ADRB2ADRB1HIF1A | |
| SCHEMBL8770959 | 0.77 | KMT2A (0.37) | MEN1KMT2ACYP2D6HDAC3HDAC1 | |
| SCHEMBL8770908 | 0.77 | CES2 (0.43) | CYP2D6ADRB1HDAC3HDAC1HDAC2 | |
| SCHEMBL8770889 | 0.77 | KMT2A (0.53) | MEN1KMT2AKCNH2CYP2D6NFKB1 | |
| SCHEMBL8771331 | 0.77 | HTT (0.42) | MEN1KMT2ACYP2D6HDAC3HDAC1 | |
| SCHEMBL8770923 | 0.77 | CES2 (0.41) | MEN1KMT2ACYP2D6ADRB2ADRB1 | |
| SCHEMBL8770864 | 0.77 | POLB (0.47) | CYP1A2ALDH1A1LMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |