Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364637 | 0.72 | KCNN4 (0.41) | MMP13ADAMTS4ADAMTS5LMNAHIF1A | |
| SCHEMBL878150 | 0.70 | CYP2C19 (0.38) | CYP1A2HIF1AALDH1A1ESR1CYP3A4 | |
| SCHEMBL877143 | 0.69 | MMP13 (0.40) | MMP12MMP13SLC6A2MMP9RAB9A | |
| SCHEMBL877681 | 0.69 | CYP2C19 (0.37) | LMNAHIF1AALDH1A1ESR1CYP3A4 | |
| SCHEMBL877145 | 0.68 | CYP2C9 (0.40) | MMP13ADAMTS4MMP9CYP1A2RAB9A | |
| SCHEMBL11822578 | 0.67 | ALDH1A1 (0.47) | FFAR1ADAMTS4ADAMTS5LMNACYP1A2 | |
| SCHEMBL13931399 | 0.65 | KCNN4 (0.48) | FFAR1LMNASMN1; SMN2HIF1ASLC6A3 | |
| SCHEMBL28846036 | 0.64 | KCNN4 (0.52) | RAB9ASMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL6188679 | 0.64 | CES1 (0.56) | SLC6A2LMNARAB9ASMN1; SMN2SLC6A3 | |
| SCHEMBL11830596 | 0.63 | ALDH1A1 (0.43) | FFAR1ADAMTS4ADAMTS5LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |