Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878151 | 0.75 | CYP1A2 (0.40) | CYP1A2 | |
| SCHEMBL877682 | 0.72 | KIF11 (0.41) | CYP1A2GAACYP2C19PTGS2SMN1; SMN2 | |
| SCHEMBL2364641 | 0.72 | KCNN4 (0.42) | CYP1A2 | |
| SCHEMBL877144 | 0.68 | MMP12 (0.38) | CYP2C9ADAMTS4MMP2MMP13MMP1 | |
| SCHEMBL11013977 | 0.65 | PTPN5 (0.36) | CYP2C9ADAMTS4CYP1A2GAAPKM | |
| SCHEMBL28846036 | 0.64 | KCNN4 (0.52) | CYP2C9NPC1RAB9ASMN1; SMN2 | |
| Biphenyl SCHEMBL27492413 | 0.63 | TSHR (0.52) | CYP2C9CYP1A2GAAPKMCYP2C19 | |
| Biphenyl SCHEMBL21462355 | 0.63 | ALDH1A1 (0.53) | ADAMTS4MMP2MMP3MMP13MMP1 | |
| SCHEMBL4827831 | 0.62 | PTGS2 (0.67) | CYP2C9CYP1A2GAAPKMCYP2C19 | |
| SCHEMBL31331542 | 0.62 | SCN9A (0.64) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |