Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | CDC25A | P30304 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | S100A4 | P26447 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CDC25C | P30307 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639269 | 0.85 | HTR7 (0.65) | HTR7CDC25ACDC25BS100A4MAPT | |
| SCHEMBL8772078 | 0.78 | S100A4 (0.61) | HTR7CDC25ACDC25BS100A4MAPT | |
| SCHEMBL8772059 | 0.77 | DPP4 (0.37) | MAPTALDH1A1HPGDMEN1LMNA | |
| SCHEMBL29594315 | 0.76 | S100A4 (0.50) | HTR7CDC25ACDC25BS100A4MAPT | |
| SCHEMBL10035839 | 0.76 | S100A4 (0.50) | HTR7CDC25ACDC25BS100A4MAPT | |
| SCHEMBL16670248 | 0.75 | POLB (0.52) | HTR7S100A4MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL13044882 | 0.71 | HTR7 (0.53) | HTR7CDC25ACDC25BS100A4MAPT | |
| SCHEMBL9712004 | 0.70 | ERN1 (0.36) | CDC25ACDC25BS100A4MAPTMAPK1 | |
| SCHEMBL25413385 | 0.70 | MAPK1 (0.41) | CDC25ACDC25BS100A4MAPTMAPK1 | |
| SCHEMBL5184972 | 0.70 | ALDH1A1 (0.45) | HTR7CDC25ACDC25BS100A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799267-A1 | NAPHTALENEDICARBOXYLIC ACID POLYMERS CONTAINING ARYL THIOETHERS AND HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019517-A1 | NAPHTALENEDICARBOXYLIC ACID POLYMERS CONTAINING ARYL THIOETHERS AND HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |