SCHEMBL8772059

SCHEMBL8772059

OCCSc1cccc(Oc2ccccc2)c1SCCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.37
TTR P02766 1/20 0.37
PTGS2 P35354 3/20 0.36
LTA4H P09960 2/20 0.36
HRH1 P35367 1/20 0.36
CTNNB1 P35222 1/20 0.36
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 2/20 0.35
RIPK1 Q13546 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
HPGD P15428 1/20 0.35
RECQL P46063 1/20 0.34
LMNA P02545 3/20 0.34
KMT2A Q03164 2/20 0.34
GAA P10253 1/20 0.34
ADRA2C P18825 1/20 0.34
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8640349 0.87 PTGS2 (0.43) TTRPTGS2LTA4HHRH1CTNNB1
SCHEMBL8772079 0.77 HTR7 (0.49) DPP4POLBMAPTALDH1A1HPGD
SCHEMBL10035839 0.71 S100A4 (0.50) PTGS2MAPTALDH1A1HPGDRECQL
SCHEMBL29594315 0.71 S100A4 (0.50) PTGS2MAPTALDH1A1HPGDRECQL
SCHEMBL10364842 0.69 MTNR1A (0.59) PTGS2ALDH1A1KMT2ATSHR
SCHEMBL17038481 0.68 PTGS2 (0.60) PTGS2LTA4HPOLBMAPTLMNA
SCHEMBL2297107 0.66 TSHR (0.46) LTA4HHRH1CTNNB1ALDH1A1RIPK1
SCHEMBL10977179 0.66 L3MBTL1 (0.43) DPP4LTA4HHRH1MAPTALDH1A1
SCHEMBL9712004 0.66 ERN1 (0.36) POLBMAPTALDH1A1HPGDRECQL
SCHEMBL25413385 0.66 MAPK1 (0.41) MAPTALDH1A1HPGDRECQLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799267-A1 NAPHTALENEDICARBOXYLIC ACID POLYMERS CONTAINING ARYL THIOETHERS AND HAVING REDUCED FLUORESCENCE EASTMAN CHEMICAL COMPANY (US) 1997-10-08 EP disclosed
WO-1996019517-A1 NAPHTALENEDICARBOXYLIC ACID POLYMERS CONTAINING ARYL THIOETHERS AND HAVING REDUCED FLUORESCENCE EASTMAN CHEMICAL COMPANY (US) 1996-06-27 WO disclosed