Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | USP9X | Q93008 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | USP5 | P45974 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892483 | 1.00 | CTH (0.36) | CTHUSP9XALDH1A1HPGDSTAT3 | |
| SCHEMBL12747839 | 0.87 | CTH (0.39) | CTHUSP9XALDH1A1HPGDSTAT3 | |
| SCHEMBL8892427 | 0.75 | USP9X (0.35) | CTHUSP9XALDH1A1HPGDSTAT3 | |
| SCHEMBL8772140 | 0.75 | USP9X (0.35) | CTHUSP9XALDH1A1HPGDSTAT3 | |
| SCHEMBL9238875 | 0.75 | ALDH1A1 (0.41) | CTHUSP9XALDH1A1HPGD | |
| SCHEMBL9236705 | 0.75 | ALDH1A1 (0.41) | CTHUSP9XALDH1A1HPGD | |
| SCHEMBL9238873 | 0.75 | ALDH1A1 (0.41) | CTHUSP9XALDH1A1HPGD | |
| SCHEMBL840645 | 0.74 | ALDH1A1 (0.39) | CTHUSP9XALDH1A1HPGDSTAT3 | |
| SCHEMBL840646 | 0.74 | ALDH1A1 (0.39) | CTHUSP9XALDH1A1HPGDSTAT3 | |
| SCHEMBL22778040 | 0.73 | CTH (0.39) | CTHUSP9XALDH1A1HPGDSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801061-A2 | Leucotrien-B4 derivatives, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-15 | — | — | EP | disclosed |
| US-5614634-A | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-03-25 | — | — | US | disclosed |
| US-5440044-A | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |
| EP-0477311-A1 | NEW LEUCOTRIENE B 4? DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-01 | — | — | EP | disclosed |
| WO-1991014676-A1 | NEW LEUCOTRIENE B4 DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-10-03 | — | — | WO | disclosed |