SCHEMBL8772292

SCHEMBL8772292

Cc1ccc2c(O)c(C(C)(C)C)cc(Cc3cc(C(C)(C)C)c(O)c4ccc(C)cc34)c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.54
CYP2C9 P11712 4/20 0.53
CYP2C19 P33261 4/20 0.53
HIF1A Q16665 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
CYP2D6 P10635 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CA2 P00918 4/20 0.46
ALDH1A1 P00352 2/20 0.46
POLB P06746 1/20 0.46
TYR P14679 1/20 0.46
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
AMY1A P0DUB6 1/20 0.42
TP53 P04637 1/20 0.39
CA1 P00915 2/20 0.38
CYP1A2 P05177 1/20 0.38
NQO1 P15559 1/20 0.36
GAA P10253 2/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772295 0.81 HSPA5 (0.50) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8772275 0.78 HSPA5 (0.47) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL722580 0.72 HSPA5 (0.77) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL9817048 0.72 SHBG (0.42) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8772303 0.71 HSPA5 (0.47) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29415372 0.71 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL34162 0.71 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29351672 0.71 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30337445 0.71 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL9128005 0.70 CA2 (0.42) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5409798-A Base layer containing polymerizable compound, photosensitive layer capable of peeling development containing different polymerizable compound, layer-forming polymer, photoinitiator, peeling support layer CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
EP-0530674-A1 Plate blank, process for producing printing plate from plate blank, and printing method and apparatus using plate CANON KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed