SCHEMBL8772303

SCHEMBL8772303

Cc1cccc2c(Cc3cc(C(C)(C)C)c(O)c4c(C)cccc34)cc(C(C)(C)C)c(O)c12

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.47
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
CYP2C9 P11712 4/20 0.46
CYP2C19 P33261 4/20 0.46
HIF1A Q16665 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
CYP2D6 P10635 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CA2 P00918 3/20 0.40
CYP1A2 P05177 1/20 0.40
SCN2A Q99250 2/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
TP53 P04637 1/20 0.37
CA1 P00915 1/20 0.36
GPR84 Q9NQS5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772295 0.78 HSPA5 (0.50) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8772275 0.78 HSPA5 (0.47) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL8762620 0.76 HSPA5 (0.46) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL9817048 0.76 SHBG (0.42) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL8762762 0.74 CA2 (0.43) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL8466821 0.73 GABRA1 (0.53) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL8772299 0.73 LMNA (0.45) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL5857645 0.73 HSPA5 (0.58) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL8762772 0.72 CA2 (0.41) HSPA5GABRA1GABRB2CYP2C9CYP2C19
SCHEMBL8772324 0.72 CYP2C9 (0.44) HSPA5GABRA1GABRB2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed