SCHEMBL8772275

SCHEMBL8772275

Cc1cc(Cc2cc(C(C)(C)C)c(O)c3ccccc23)c2ccccc2c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
CYP2C9 P11712 4/20 0.46
CYP2C19 P33261 4/20 0.46
HIF1A Q16665 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
CYP2D6 P10635 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PKM P14618 1/20 0.45
HMGB1 P09429 1/20 0.44
CXCL12 P48061 1/20 0.44
CYP1A2 P05177 1/20 0.43
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
CA2 P00918 3/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772295 0.92 HSPA5 (0.50) HSPA5LMNACYP2C9CYP2C19HIF1A
SCHEMBL8772299 0.88 LMNA (0.45) HSPA5LMNAHTTCYP2C9CYP2C19
SCHEMBL9817048 0.88 SHBG (0.42) HSPA5LMNAHTTCYP2C9CYP2C19
SCHEMBL8772324 0.87 CYP2C9 (0.44) HSPA5LMNAHTTCYP2C9CYP2C19
SCHEMBL1151311 0.87 HTT (0.61) LMNAHTTPKMHMGB1CXCL12
SCHEMBL9128005 0.82 CA2 (0.42) HSPA5LMNAHTTCYP2C9CYP2C19
SCHEMBL14176601 0.80 HTT (0.53) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8762782 0.80 HSPA5 (0.46) HSPA5LMNACYP2C9CYP2C19HIF1A
SCHEMBL8772290 0.80 KEAP1 (0.45) HSPA5HMGB1CXCL12MEN1GAA
SCHEMBL9172537 0.79 HTT (0.56) HSPA5LMNAHTTSMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed