Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744441 | 0.96 | KIF11 (0.58) | KIF11KCNH2CA12CA1CA2 | |
| Tetramethylammonium Ion SCHEMBL3452711 | 0.93 | KIF11 (0.55) | KIF11KCNH2CA12CA1CA2 | |
| SCHEMBL1618139 | 0.79 | KIF11 (0.60) | KIF11KCNH2CA12CA1CA2 | |
| SCHEMBL3185263 | 0.78 | KIF11 (0.58) | KIF11KCNH2ALDH1A1 | |
| SCHEMBL10877618 | 0.75 | KIF11 (0.73) | KIF11KCNH2ALDH1A1LMNAHTT | |
| SCHEMBL7706703 | 0.75 | KIF11 (0.73) | KIF11KCNH2ALDH1A1LMNAHTT | |
| SCHEMBL8772313 | 0.74 | KIF11 (0.59) | KIF11KCNH2 | |
| SCHEMBL15212059 | 0.74 | KIF11 (0.71) | KIF11KCNH2LMNAHTT | |
| SCHEMBL22150730 | 0.74 | KIF11 (0.71) | KIF11KCNH2LMNAHTT | |
| SCHEMBL7708779 | 0.73 | KIF11 (0.69) | KIF11KCNH2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387087-B1 | Photoinitiator compositions, photohardenable compositions and photosensitive microcapsules | CYCOLOR INC (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5230982-A | Heterocyclic disulfides for crosslinking | THE MEAD CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0387087-A2 | Photoinitiator compositions, photohardenable compositions and photosensitive microcapsules | THE MEAD CORPORATION (US) | 1990-09-12 | — | — | EP | disclosed |