Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.41 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.41 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 8/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772316 | 0.96 | KIF11 (0.58) | KIF11KCNH2CA12CA1CA2 | |
| Tetramethylammonium Ion SCHEMBL3452711 | 0.93 | KIF11 (0.55) | KIF11KCNH2CA12CA1CA2 | |
| SCHEMBL1618139 | 0.79 | KIF11 (0.60) | KIF11KCNH2CA12CA1CA2 | |
| SCHEMBL3185263 | 0.78 | KIF11 (0.58) | KIF11KCNH2ALDH1A1 | |
| SCHEMBL10877618 | 0.75 | KIF11 (0.73) | KIF11KCNH2ALDH1A1LMNAHTT | |
| SCHEMBL7706703 | 0.75 | KIF11 (0.73) | KIF11KCNH2ALDH1A1LMNAHTT | |
| SCHEMBL7747170 | 0.74 | KIF11 (0.59) | KIF11KCNH2 | |
| SCHEMBL15212059 | 0.74 | KIF11 (0.71) | KIF11KCNH2LMNAHTT | |
| SCHEMBL22150730 | 0.74 | KIF11 (0.71) | KIF11KCNH2LMNAHTT | |
| SCHEMBL5528724 | 0.73 | KIF11 (0.53) | KIF11KCNH2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6190824-B1 | POLYMERIZABLE MONOMER, A PHOTOPOLYMERIZATION INITIATOR, AND A DIAZONIUM SALT HAVING A SPECIFIC, BORON ANION PORTION | FUJI PHOTO FILM CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0599993-B1 | A HARD COPY IMAGING SYSTEM | EASTMAN KODAK CO (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0339841-B1 | Photosensitive compositions and materials | MEAD CORP (US) | 1995-07-05 | — | — | EP | disclosed |
| EP-0389067-B1 | Ionic dye compounds | MEAD CORP (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0599993-A1 | A HARD COPY IMAGING SYSTEM. | EASTMAN KODAK CO (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5252425-A | Hard copy imaging system | EASTMAN KODAK COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| WO-1993003927-A1 | A HARD COPY IMAGING SYSTEM | EASTMAN KODAK COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5151520-A | Cyanine, carbocyanine, hemicyanine, rhodamine and azamethine dyes | THE MEAD CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-5035621-A | Photohardenable Dental Adhesive | MEAD CORPORATION (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0434437-A2 | Photohardenable or thermohardenable compositions and photosensitive materials utilising such photohardenable compositions | THE MEAD CORPORATION (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4865942-A | CYANINE DYES | THE MEAD CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |
| US-4842980-A | ABSORBING ACTINIC RADIATION AND PRODUCING FREE RADICALS | THE MEAD CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0301769-A2 | Radiation-curable compositions and their use for printing and coating | THE MEAD CORPORATION (US) | 1989-02-01 | — | — | EP | disclosed |
| US-4801392-A | FREE RADICAL POLYMERIZATION OR CROSSLINKING | THE MEAD CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| US-4800149-A | FREE RADICAL GENERATION AND CROSSLINKING | THE MEAD CORPORATION (US) | 1989-01-24 | — | — | US | disclosed |
| US-4788124-A | IONIC DYE-REACTIVE COUNTER ION COMPOUND | THE MEAD CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4772530-A | XANTHENE AND OXONOL DYES | THE MEAD CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4772541-A | SENSITIVE AT LONGER WAVELENGTHS | THE MEAD CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0277034-A2 | Lamination of two substrates | THE MEAD CORPORATION (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4751102-A | FOR PHOTOHARDENABLE FREE RADICAL ADDITION POLYMERIZABLE OR CROSSLINKABLE COMPOUND | THE MEAD CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |