SCHEMBL8772369

SCHEMBL8772369

CCc1cc(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2ccccc2c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.49
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 2/20 0.46
DHFR P00374 1/20 0.43
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
BLM P54132 2/20 0.41
ATM Q13315 2/20 0.41
HIF1A Q16665 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 2/20 0.41
USP2 O75604 1/20 0.41
CYP2D6 P10635 1/20 0.41
HMGB1 P09429 1/20 0.41
CXCL12 P48061 1/20 0.41
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772299 0.84 LMNA (0.45) HSPA5MEN1KMT2AGAADHFR
SCHEMBL8772297 0.81 HMGB1 (0.58) MEN1KMT2AMAPTHMGB1CXCL12
SCHEMBL8772324 0.80 CYP2C9 (0.44) HSPA5MEN1KMT2AGAADHFR
SCHEMBL8762782 0.80 HSPA5 (0.46) HSPA5MEN1KMT2AGAAALDH1A1
SCHEMBL30464059 0.80 HSPA5 (0.53) HSPA5MEN1KMT2AGAADHFR
SCHEMBL28384212 0.80 HSPA5 (0.53) HSPA5MEN1KMT2AGAADHFR
SCHEMBL8962592 0.79 KEAP1 (0.47) HMGB1CXCL12
SCHEMBL9817048 0.78 SHBG (0.42) HSPA5DHFRCYP1A2HIF1ACYP2D6
SCHEMBL8772295 0.78 HSPA5 (0.50) HSPA5MEN1KMT2AGAAALDH1A1
SCHEMBL18902069 0.78 HSPA5 (0.71) HSPA5MEN1KMT2AGAADHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed