SCHEMBL8772386

SCHEMBL8772386

Cc1c(O)ccc2c1Oc1c(ccc(O)c1C)C2c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.36
ESR2 Q92731 5/20 0.36
ESR1 P03372 4/20 0.36
ALOX5 P09917 1/20 0.36
TRPA1 O75762 1/20 0.35
ATM Q13315 1/20 0.35
KDM4E B2RXH2 4/20 0.35
HSD17B10 Q99714 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 2/20 0.35
POLB P06746 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
IDO1 P14902 1/20 0.35
DRD1 P21728 3/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3278459 0.71 ALOX5 (0.51) GAAALOX5MEN1KMT2AALDH1A1
SCHEMBL18644308 0.68 MYB (0.36) GAAESR2ESR1MEN1KMT2A
Phenol SCHEMBL28146909 0.66 CA12 (0.42) GAAESR2ESR1TRPA1ATM
Phenol SCHEMBL5049852 0.66 CA12 (0.42) GAAESR2ESR1TRPA1ATM
SCHEMBL10228448 0.65 IGF1R (0.44) GAAKDM4EHSD17B10MEN1KMT2A
SCHEMBL11435566 0.64 MEN1 (0.45) GAAKDM4EHSD17B10MEN1KMT2A
SCHEMBL2614948 0.64 GAA (0.53) GAAKDM4EHSD17B10MEN1KMT2A
SCHEMBL19851151 0.64 MEN1 (0.64) GAAESR2ESR1HSD17B10MEN1
SCHEMBL15688238 0.64 GAA (0.41) GAAESR2ESR1KDM4EHSD17B10
SCHEMBL13019593 0.63 PRMT1 (0.42) GAAESR2HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed