Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | NAAA | Q02083 | 4/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766870 | 0.88 | TRPA1 (0.42) | TRPA1TRPV1FAAHNAAAPTGER4 | |
| SCHEMBL8767631 | 0.84 | LMNA (0.40) | FAAHPTGER4LMNA | |
| SCHEMBL8767268 | 0.79 | TRPA1 (0.41) | TRPA1TRPV1FAAHNAAAPTGER4 | |
| SCHEMBL8766792 | 0.78 | TRPA1 (0.40) | TRPA1TRPV1FAAHNAAAPTGER4 | |
| SCHEMBL8772394 | 0.78 | TRPA1 (0.40) | TRPA1TRPV1FAAHNAAAPTGER4 | |
| SCHEMBL8772451 | 0.78 | LMNA (0.40) | LMNA | |
| SCHEMBL8767549 | 0.73 | LMNA (0.39) | FAAHLMNA | |
| SCHEMBL8552278 | 0.72 | HMOX1 (0.48) | TRPA1LMNA | |
| SCHEMBL6823573 | 0.72 | HDAC1 (0.56) | — | |
| SCHEMBL8772367 | 0.67 | LMNA (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |