Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772451 | 0.76 | LMNA (0.40) | LMNAALDH1A1KDM4EPOLBCYP1A2 | |
| SCHEMBL8772464 | 0.72 | KMT2A (0.45) | L3MBTL1MEN1KMT2A | |
| SCHEMBL8766432 | 0.67 | HTT (0.40) | LMNAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL8772426 | 0.67 | TRPA1 (0.41) | LMNA | |
| SCHEMBL18165400 | 0.65 | EPHX1 (0.62) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1GAA | |
| SCHEMBL18165401 | 0.65 | EPHX1 (0.62) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1GAA | |
| SCHEMBL8552278 | 0.65 | HMOX1 (0.48) | LMNAALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8767339 | 0.64 | HTT (0.38) | LMNAALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8553752 | 0.64 | CACNA2D1 (0.40) | LMNAPOLBCYP2C9HTTL3MBTL1 | |
| SCHEMBL9708647 | 0.64 | ALDH1A1 (0.51) | LMNAALDH1A1CYP1A2CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |