Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709935 | 0.80 | RAB9A (0.40) | KCNMA1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8709931 | 0.80 | RAB9A (0.40) | KCNMA1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8715621 | 0.80 | ERN1 (0.47) | KCNMA1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8713136 | 0.78 | MEN1 (0.48) | KCNMA1ALDH1A1HPGDSMN1; SMN2KDR | |
| SCHEMBL8712961 | 0.78 | RAB9A (0.43) | KCNMA1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8712965 | 0.78 | RAB9A (0.43) | KCNMA1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL29848306 | 0.77 | CA1 (0.67) | KCNMA1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL552216 | 0.77 | CA1 (0.67) | KCNMA1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7821603 | 0.73 | KDM4E (0.54) | ALDH1A1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL773980 | 0.73 | PARP1 (0.58) | ALDH1A1HPGDRAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |