Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362615 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL13505435 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL8669451 | 0.81 | CA2 (0.46) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL11781793 | 0.79 | CHEK1 (0.44) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL1710167 | 0.79 | LMNA (0.59) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL1870853 | 0.79 | LMNA (0.59) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL12633216 | 0.79 | LMNA (0.59) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL20902631 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL8672113 | 0.74 | ALDH1A1 (0.41) | KDM4EALDH1A1L3MBTL1GLAMAPT | |
| SCHEMBL9358558 | 0.74 | ALDH1A1 (0.41) | KDM4EALDH1A1L3MBTL1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873168-B1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORP (JP) | 2012-12-12 | — | — | EP | claimed |
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | claimed |
| EP-0510410-B1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE FIRESTONE INC (US) | 1996-06-12 | — | — | EP | claimed |
| EP-0451604-B1 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE FIRESTONE INC (US) | 1994-12-21 | — | — | EP | claimed |
| JP-8269131-A | — | — | None | — | — | JP | disclosed |
| CN-111051361-B | Rubber composition | 株式会社LG化学 | 2023-06-20 | — | — | CN | disclosed |
| EP-3715388-B1 | MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEMICAL LTD (KR) | 2023-04-26 | — | — | EP | disclosed |
| CN-111344314-B | Modified conjugated diene polymer and preparation method thereof | 株式会社LG化学 | 2023-01-03 | — | — | CN | disclosed |
| US-11421053-B2 | Conjugated diene-based polymer and method for preparing the same | LG CHEM, LTD. | 2022-08-23 | — | — | US | disclosed |
| CN-111051361-A | Rubber composition | 株式会社LG化学 | 2020-04-21 | — | — | CN | disclosed |
| JP-H08269131-A | DIENE POLYMER AND COPOLYMER TERMINATED BY REACTION WITH N-ALKYL AND N-ARYLIMINE | BRIDGESTONE CORP | 1996-10-15 | — | — | JP | disclosed |
| EP-0451603-B1 | Elastomers and products having reduced hysteresis | BRIDGESTONE FIRESTONE INC (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5354822-A | Endcapping the addition polymerization with a reaction product of an aldimines, a ketimines, a secondary amines and an organo lithium compound prior quenching | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-10-11 | — | — | US | disclosed |
| US-5268413-A | Blend of functionalized polymer and organolithium compound | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-12-07 | — | — | US | disclosed |
| US-5153159-A | ELASTOMERS AND PRODUCTS HAVING REDUCED HYSTERESIS | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0451603-A2 | Elastomers and products having reduced hysteresis | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |