Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672113 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL6567757 | 0.80 | C5AR1 (0.37) | ALDH1A1KDM4ELMNAHPGDSMN1; SMN2 | |
| SCHEMBL8066324 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL9362615 | 0.74 | KDM4E (0.49) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL8773372 | 0.74 | KDM4E (0.49) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL1710167 | 0.72 | LMNA (0.59) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL1870853 | 0.72 | LMNA (0.59) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL12633216 | 0.72 | LMNA (0.59) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL11371193 | 0.71 | LMNA (0.44) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL8672110 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451604-B1 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE FIRESTONE INC (US) | 1994-12-21 | — | — | EP | claimed |