Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985638 | 0.87 | MTNR1A (0.55) | MTNR1ACNR1CNR2CYP2D6RAB9A | |
| Hydrogen Sulfide SCHEMBL27855781 | 0.84 | CA12 (0.44) | HTR1ACYP2D6SLC6A4MAOAMAOB | |
| SCHEMBL11880562 | 0.79 | PTPN1 (0.58) | MTNR1ACYP2D6MAOAMAOBALDH1A1 | |
| SCHEMBL30649150 | 0.76 | ALDH1A1 (0.59) | CYP2D6MAOAMAOBNPC1ALDH1A1 | |
| SCHEMBL8773392 | 0.76 | ALDH1A1 (0.59) | CYP2D6MAOAMAOBNPC1ALDH1A1 | |
| SCHEMBL8773399 | 0.73 | MAOA (0.52) | MTNR1AHTR1ACYP2D6SLC6A4MAOA | |
| SCHEMBL11878491 | 0.71 | PTPN1 (0.56) | MTNR1ACYP2D6MAOAMAOBALDH1A1 | |
| SCHEMBL13126879 | 0.71 | TP53 (0.52) | MTNR1ARAB9AMAOBALDH1A1TP53 | |
| SCHEMBL12386447 | 0.71 | MTNR1A (0.48) | MTNR1ARAB9AMAOBNPC1ALDH1A1 | |
| SCHEMBL11727575 | 0.71 | MAOA (0.56) | HTR1ACYP2D6RAB9AMAOANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | HTR1D, HTR1A, HTR1B | MTNR1A 151/4885CNR1 91/4885CNR2 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.