SCHEMBL8773706

SCHEMBL8773706

O=C(O)Cc1cc(I)c(O)c(I)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.71
THRA P10827 5/20 0.71
PPARG P37231 4/20 0.71
RXRA P19793 3/20 0.71
ITGB3 P05106 1/20 0.71
ITGAV P06756 1/20 0.71
HSD17B10 Q99714 5/20 0.51
LMNA P02545 4/20 0.51
HIF1A Q16665 3/20 0.51
HPGD P15428 3/20 0.51
CYP2C9 P11712 3/20 0.51
ADORA3 P0DMS8 3/20 0.51
PDE4D Q08499 3/20 0.51
POLB P06746 2/20 0.51
CYP1A2 P05177 2/20 0.51
PGR P06401 2/20 0.51
HTR1A P08908 2/20 0.51
HTR2B P41595 2/20 0.51
ABCB11 O95342 1/20 0.51
CHRM2 P08172 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643075 0.86 THRB (0.57) THRBTHRAPPARGRXRAITGB3
SCHEMBL5012985 0.86 THRA (0.60) THRBTHRAPPARGRXRAITGB3
Tetrac SCHEMBL365951 0.84 THRB (1.00) THRBTHRAPPARGRXRAITGB3
SCHEMBL1527125 0.83 ERN1 (0.55) THRBTHRAPPARGRXRAITGB3
SCHEMBL5928042 0.83 THRB (0.53) THRBTHRAPPARGRXRAITGB3
SCHEMBL30448708 0.80 THRA (0.51) THRBTHRAPPARGRXRAITGB3
SCHEMBL378767 0.80 THRA (0.51) THRBTHRAPPARGRXRAITGB3
SCHEMBL10962553 0.80 THRB (0.50) THRBTHRAPPARGRXRAITGB3
SCHEMBL12837302 0.79 THRB (0.89) THRBTHRAPPARGRXRAITGB3
SCHEMBL12837223 0.79 THRB (0.83) THRBTHRAPPARGRXRAITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030983-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-07-09 US disclosed
EP-3394024-B1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES UNIV RUTGERS (US) 2023-08-02 EP disclosed
US-20230167238-A1 POLYMETRIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-06-01 US disclosed
US-11649203-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-05-16 US disclosed
US-20220002478-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-01-06 US disclosed
US-11124603-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-09-21 US disclosed
WO-2021163520-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-08-19 WO disclosed
US-20200369597-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-11-26 US disclosed
US-10774030-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-09-15 US disclosed
EP-3312155-B1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES UNIV RUTGERS (US) 2020-08-05 EP disclosed
EP-3394024-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES Rutgers, The State University of New Jersey (US) 2018-10-31 EP disclosed
EP-3312155-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES Rutgers, The State University of New Jersey (US) 2018-04-25 EP disclosed
EP-2809702-B1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES UNIV RUTGERS (US) 2017-12-20 EP disclosed
WO-2017111994-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-06-29 WO disclosed
US-20160376401-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2016-12-29 US disclosed
US-9416090-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-08-16 US disclosed
US-20130203713-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-08-08 US disclosed
EP-0802798-A1 METHOD AND COMPOSITIONS FOR INCREASING THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE AGENTS CHIRON CORPORATION (US) 1997-10-29 EP disclosed
WO-1995022992-A1 METHOD AND COMPOSITIONS FOR INCREASING THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE AGENTS CHIRON CORPORATION (US) 1995-08-31 WO disclosed
US-5273885-A Using a polyiodothyronine analog of a phenyl compound containing a hydroxyl group ortho to an iodine SYNTEX (U.S.A.) INC. (US) 1993-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203713-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, MYB THRB 3226/4885THRA 2566/4885PPARG 1129/4885
US-12030983-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, MYB THRB 3084/4885THRA 2478/4885PPARG 1026/4885
US-11124603-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, MYB THRB 3226/4885THRA 2566/4885PPARG 1129/4885
US-20220002478-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, MYB THRB 3084/4885THRA 2478/4885PPARG 1026/4885
US-10774030-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, HPD THRB 1124/4885THRA 778/4885PPARG 2682/4885
US-20200369597-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, TYRO3 THRB 1884/4885THRA 1319/4885PPARG 2712/4885
US-20160376401-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, MYB THRB 3226/4885THRA 2566/4885PPARG 1129/4885
US-11649203-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, TYRO3 THRB 1884/4885THRA 1319/4885PPARG 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.