Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639322 | 0.79 | SMN1; SMN2 (0.62) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL8773761 | 0.78 | MEN1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL8635989 | 0.76 | SMN1; SMN2 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL7409264 | 0.74 | SMN1; SMN2 (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL28619865 | 0.74 | KMT2A (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL17842262 | 0.74 | RAB9A (0.75) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL8773766 | 0.73 | KMT2A (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL8641254 | 0.73 | SMN1; SMN2 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL7132085 | 0.73 | LTA4H (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9ALTA4H | |
| SCHEMBL8640087 | 0.72 | SMN1; SMN2 (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804427-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996011192-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-04-18 | — | — | WO | disclosed |