Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876846 | 0.89 | EGFR (0.49) | MEN1KMT2AABCG2MAPTKDM4E | |
| SCHEMBL1726552 | 0.84 | ABCG2 (0.53) | MEN1KMT2AABCG2MAPTKDM4E | |
| SCHEMBL878154 | 0.83 | MEN1 (0.60) | MEN1KMT2AABCG2MAPTKDM4E | |
| SCHEMBL4782453 | 0.83 | ABCG2 (0.53) | MEN1KMT2AABCG2MAPTKDM4E | |
| SCHEMBL4784466 | 0.82 | ABCG2 (0.50) | MEN1KMT2AABCG2MAPTKDM4E | |
| SCHEMBL878196 | 0.82 | ROCK2 (0.68) | TGFBR1CLK4 | |
| SCHEMBL877685 | 0.81 | JAK3 (0.53) | MEN1KMT2AABCG2MAPTKDM4E | |
| SCHEMBL877614 | 0.80 | ABCG2 (0.68) | MEN1KMT2AABCG2MAPTABCB1 | |
| SCHEMBL877613 | 0.80 | ABCG2 (0.68) | MEN1KMT2AABCG2MAPTABCB1 | |
| SCHEMBL3792745 | 0.79 | KDM1A (0.47) | MEN1KMT2AABCG2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040499-A2 | METABOLIC INHIBITORS | SURFACE LOGIX, INC. (US) | 2012-03-29 | — | — | WO | disclosed |