Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 11/20 | 0.49 |
| ▸ | MMP3 | P08254 | 8/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773895 | 0.95 | MME (0.54) | MMEMMP2MMP3MMP7MMP1 | |
| SCHEMBL4634106 | 0.82 | MMP1 (0.70) | MMP2MMP3MMP7MMP1MMP9 | |
| SCHEMBL4634107 | 0.82 | MMP1 (0.70) | MMP2MMP3MMP7MMP1MMP9 | |
| SCHEMBL27573505 | 0.82 | MMP1 (0.70) | MMP2MMP3MMP7MMP1MMP9 | |
| SCHEMBL9066930 | 0.82 | BIRC2 (0.46) | MMEMMP3MMP9 | |
| SCHEMBL8773906 | 0.81 | MME (0.55) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL5400156 | 0.81 | GRIK1 (0.54) | MMP2MMP3MMP1MMP9 | |
| SCHEMBL5400150 | 0.81 | GRIK1 (0.54) | MMP2MMP3MMP1MMP9 | |
| SCHEMBL8469705 | 0.81 | MMP2 (0.50) | MMP2MMP3MMP7MMP1MMP9 | |
| SCHEMBL6834457 | 0.80 | GRIK1 (0.52) | MMP2MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793643-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016027-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-05-30 | — | — | WO | disclosed |