Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | RRM2 | P31350 | 1/20 | 0.41 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773906 | 0.89 | MME (0.55) | MMEMMP9CTSSCTSKCTSL | |
| SCHEMBL8773895 | 0.83 | MME (0.54) | MMEMMP3MMP9 | |
| SCHEMBL8773904 | 0.82 | MME (0.53) | MMEMMP3MMP9 | |
| SCHEMBL8773913 | 0.79 | LTA4H (0.49) | MMP3CTSSCTSKKMT2A | |
| SCHEMBL7051239 | 0.77 | HDAC1 (0.54) | CTSSCTSKMEN1KMT2AFOLH1 | |
| SCHEMBL16798232 | 0.77 | HDAC1 (0.54) | CTSSCTSKMEN1KMT2AFOLH1 | |
| SCHEMBL6448846 | 0.77 | HDAC1 (0.54) | CTSSCTSKMEN1KMT2AFOLH1 | |
| SCHEMBL3823691 | 0.76 | CTSK (0.60) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL7400657 | 0.75 | CYP1A2 (0.48) | CTSSCTSK | |
| SCHEMBL31199022 | 0.75 | SLC7A5 (0.42) | MMECTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |