Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.50 |
| ▸ | MMP7 | P09237 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.47 |
| ▸ | MMP3 | P08254 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828120 | 0.92 | MMP2 (0.59) | MMP2MMP7MMP9MMP1MMP3 | |
| SCHEMBL6294116 | 0.88 | MMP2 (0.62) | MMP2MMP7ACEBIRC2MMP1 | |
| SCHEMBL8468208 | 0.82 | BIRC2 (0.46) | MMP2MMP7MMP9ACEBIRC2 | |
| SCHEMBL8773904 | 0.81 | MME (0.53) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL8828135 | 0.80 | MMP3 (0.72) | MMP2MMP7MMP9MMP1MMP3 | |
| SCHEMBL8828128 | 0.80 | MMP1 (0.72) | MMP2MMP7MMP9MMP1MMP3 | |
| SCHEMBL8773895 | 0.80 | MME (0.54) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL8055025 | 0.79 | MMP2 (0.77) | MMP2MMP7MMP9MMP1MMP3 | |
| SCHEMBL8828145 | 0.79 | MMP2 (0.61) | MMP2MMP7MMP9MMP1MMP3 | |
| SCHEMBL4289468 | 0.79 | ACE (0.54) | MMP2MMP7MMP9MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749302-A4 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP INC (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0749302-A1 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995022966-A1 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP, INC. (US) | 1995-08-31 | — | — | WO | disclosed |