Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 11/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773906 | 0.83 | MME (0.55) | CTSSCTSKKMT2AMMP2 | |
| SCHEMBL9622584 | 0.82 | LTA4H (0.52) | LTA4HKMT2ARENMMP1MMP2 | |
| SCHEMBL9622591 | 0.82 | LTA4H (0.52) | LTA4HKMT2ARENMMP1MMP2 | |
| SCHEMBL9067212 | 0.82 | LTA4H (0.47) | LTA4HKMT2ARENBCHEMMP1 | |
| SCHEMBL7385076 | 0.82 | REN (0.44) | LTA4HCTSSCTSKREN | |
| SCHEMBL5488356 | 0.81 | LTA4H (0.47) | LTA4HCTSSCTSKKMT2AMMP1 | |
| SCHEMBL5488359 | 0.81 | LTA4H (0.47) | LTA4HCTSSCTSKKMT2AMMP1 | |
| SCHEMBL14492872 | 0.81 | LTA4H (0.46) | LTA4HCTSSCTSKKMT2AREN | |
| SCHEMBL7385072 | 0.81 | REN (0.56) | REN | |
| SCHEMBL1914687 | 0.80 | CTSK (0.45) | LTA4HCTSSCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793643-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016027-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-05-30 | — | — | WO | disclosed |