Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773924 | 0.80 | CRHBP (0.39) | ALDH1A1SMN1; SMN2ARKDM4EMEN1 | |
| SCHEMBL8773928 | 0.80 | CRHBP (0.39) | ALDH1A1SMN1; SMN2ARKDM4EMEN1 | |
| SCHEMBL9057515 | 0.76 | AR (0.50) | ALDH1A1ARKDM4EMEN1KMT2A | |
| SCHEMBL1873510 | 0.69 | ALDH1A1 (0.50) | CYP19A1MGLLALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5297525 | 0.65 | GAA (0.39) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL21247872 | 0.65 | ALDH1A1 (0.67) | MGLLALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23923878 | 0.64 | ALDH1A1 (0.53) | MGLLALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10882419 | 0.62 | MGLL (0.56) | MGLLALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21800144 | 0.62 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL1970979 | 0.62 | NPSR1 (0.40) | CYP19A1MGLLALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |