SCHEMBL8773968

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30353838	0.91	ALDH1A1 (0.42)	KMT2AALDH1A1HSD17B10TDP1MAPT
	SCHEMBL11039359	0.91	ALDH1A1 (0.42)	KMT2AALDH1A1HSD17B10TDP1MAPT
	SCHEMBL776395	0.81	GABRA1 (0.42)	GABRA1GABRB2CTSBPSIP1KMT2A
	SCHEMBL27453156	0.80	PNMT (0.46)	ALDH1A1HSD17B10TDP1MAPT
	SCHEMBL15621620	0.80	FAAH (0.35)	KMT2AALDH1A1HSD17B10TDP1MAPT
	SCHEMBL1428960	0.80	ALDH1A1 (0.47)	KMT2AALDH1A1LMNAPOLBTSHR
	SCHEMBL9256894	0.79	GABRA1 (0.41)	GABRA1GABRB2CTSBPSIP1MGLL
	SCHEMBL5963	0.77	ALDH1A1 (0.55)	KMT2AALDH1A1HSD17B10MAPTLMNA
	SCHEMBL3316536	0.77	GABRA1 (0.39)	GABRA1GABRB2CTSBPSIP1MGLL
	SCHEMBL11365142	0.77	GABRA1 (0.50)	GABRA1GABRB2CTSBPSIP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.