Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 13/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774435 | 0.96 | ACACB (0.40) | ACACBHSD17B10 | |
| SCHEMBL8775170 | 0.95 | CYP2D6 (0.46) | MCHR1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8774602 | 0.91 | ACACB (0.39) | ACACBRAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8775031 | 0.90 | CYP11B1 (0.39) | MCHR1ACACBRAB9AALDH1A1HPGD | |
| SCHEMBL8774095 | 0.88 | NR5A1 (0.41) | ACACBRAB9AALDH1A1HPGDCYP3A4 | |
| SCHEMBL8774805 | 0.85 | NQO1 (0.41) | ACACB | |
| SCHEMBL9157720 | 0.83 | MCHR1 (0.42) | MCHR1ACACBACACARAB9AALDH1A1 | |
| SCHEMBL8774994 | 0.82 | FFAR1 (0.42) | ACACBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL8774750 | 0.81 | FFAR1 (0.38) | ACACBRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL8774590 | 0.80 | ACACB (0.45) | ACACBACACARAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |