Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774237 | 0.96 | HSD17B10 (0.42) | FFAR1MCHR1L3MBTL1NPC1RAB9A | |
| SCHEMBL8774695 | 0.91 | FFAR1 (0.43) | FFAR1MCHR1TDP1ALDH1A1ACACB | |
| SCHEMBL8774556 | 0.85 | EGLN1 (0.47) | FFAR1L3MBTL1TDP1ALDH1A1LMNA | |
| SCHEMBL8774397 | 0.84 | NPC1 (0.47) | MCHR1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8774773 | 0.82 | ALDH1A1 (0.50) | MCHR1L3MBTL1NPC1MAPK1RAB9A | |
| SCHEMBL9159057 | 0.81 | FFAR1 (0.61) | FFAR1MCHR1NFKB1L3MBTL1TSHR | |
| SCHEMBL8774663 | 0.80 | SMN1; SMN2 (0.45) | CTRCNFKB1L3MBTL1NPC1MAPK1 | |
| SCHEMBL9472946 | 0.80 | KCNH2 (0.51) | MCHR1CTRCSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8774503 | 0.79 | SPHK1 (0.42) | FFAR1 | |
| SCHEMBL8774497 | 0.78 | ACACB (0.43) | MCHR1NFKB1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |