Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774897 | 0.96 | FFAR1 (0.45) | FFAR1HSD17B10NPC1RAB9ATP53 | |
| SCHEMBL8774460 | 0.92 | HSD17B10 (0.43) | FFAR1HSD17B10NPC1RAB9ATP53 | |
| SCHEMBL8775133 | 0.91 | HSD17B10 (0.49) | FFAR1HSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8774517 | 0.89 | EGLN1 (0.44) | FFAR1ACACBEGLN1 | |
| SCHEMBL8774677 | 0.87 | FFAR1 (0.43) | FFAR1HSD17B10RAB9APKMSMN1; SMN2 | |
| SCHEMBL8774719 | 0.85 | HSD17B10 (0.44) | FFAR1HSD17B10RAB9ATP53SMN1; SMN2 | |
| SCHEMBL8774154 | 0.84 | EGLN1 (0.47) | FFAR1ACACBEGLN1 | |
| SCHEMBL8775052 | 0.82 | RAB9A (0.48) | HSD17B10NPC1RAB9ATP53PKM | |
| SCHEMBL8774871 | 0.82 | RAB9A (0.48) | HSD17B10NPC1RAB9ATP53PKM | |
| SCHEMBL9154491 | 0.81 | GRM5 (0.44) | FFAR1HSD17B10NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |