Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776039 | 0.96 | CASR (0.53) | CASRTSHRSMN1; SMN2TBXAS1THRB | |
| SCHEMBL8775822 | 0.83 | TBXAS1 (0.55) | CASRSMN1; SMN2TBXAS1ALDH1A1MEN1 | |
| SCHEMBL8776092 | 0.78 | TBXAS1 (0.58) | CASRSMN1; SMN2TBXAS1ALDH1A1LMNA | |
| SCHEMBL8775765 | 0.78 | ROCK2 (0.48) | CASRTSHRSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL8776013 | 0.77 | TBXAS1 (0.56) | CASRSMN1; SMN2TBXAS1ALDH1A1LMNA | |
| SCHEMBL8776110 | 0.77 | TBXAS1 (0.56) | TBXAS1EPHX2 | |
| SCHEMBL8775932 | 0.75 | TBXAS1 (0.53) | CASRSMN1; SMN2TBXAS1MEN1LMNA | |
| SCHEMBL8776095 | 0.75 | TBXAS1 (0.64) | SMN1; SMN2TBXAS1LMNAHTTEPHX2 | |
| SCHEMBL8775780 | 0.75 | TBXAS1 (0.64) | SMN1; SMN2TBXAS1LMNAHTTEPHX2 | |
| SCHEMBL8775884 | 0.75 | TBXAS1 (0.64) | SMN1; SMN2TBXAS1LMNAHTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |