Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775912 | 0.81 | CA12 (0.41) | SMN1; SMN2LMNAHTT | |
| SCHEMBL8776039 | 0.79 | CASR (0.53) | SMN1; SMN2TSHRTHRBUSP2ALDH1A1 | |
| SCHEMBL8775952 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL8775982 | 0.78 | CASR (0.51) | SMN1; SMN2TSHRTHRBALDH1A1KDM4E | |
| SCHEMBL8775947 | 0.75 | MAPK1 (0.47) | SMN1; SMN2MAPK1LMNAMAPTHTT | |
| SCHEMBL8775896 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2TSHRUSP2ALDH1A1NPSR1 | |
| SCHEMBL8775901 | 0.71 | ALDH1A1 (0.47) | SMN1; SMN2TSHRALDH1A1RAB9AHTT | |
| SCHEMBL8775797 | 0.70 | MMP1 (0.45) | SMN1; SMN2TSHRALDH1A1GAALMNA | |
| SCHEMBL11146506 | 0.70 | ALDH1A1 (0.66) | USP2ALDH1A1NPSR1RAB9ACASR | |
| SCHEMBL6567020 | 0.69 | KDM4E (0.51) | SMN1; SMN2TSHRALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |