Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666557 | 0.85 | NPC1 (0.51) | HDAC1HDAC6CNR1CNR2NPC1 | |
| SCHEMBL21254776 | 0.83 | RAB9A (0.50) | HDAC1HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1666561 | 0.81 | HDAC6 (0.50) | HDAC1HDAC6CNR1CNR2NPC1 | |
| SCHEMBL1664451 | 0.77 | NPC1 (0.47) | HDAC1HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7715882 | 0.77 | RAB9A (0.53) | HDAC1HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1664779 | 0.75 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL8772126 | 0.73 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL1664454 | 0.73 | RAB9A (0.52) | HDAC1HDAC6NPC1RAB9AHDAC3 | |
| SCHEMBL1665100 | 0.73 | HPGDS (0.54) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL4528298 | 0.72 | TBK1 (0.56) | HDAC1HDAC6NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |