Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Glutaral. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutaral SCHEMBL9851211 | 1.00 | HIF1A (0.56) | HIF1ATSHRTRPV1MAPTFAAH | |
| Glutaral SCHEMBL1359455 | 0.94 | HIF1A (0.56) | HIF1ATSHRTRPV1MAPTFAAH | |
| Glutaral SCHEMBL456725 | 0.94 | HIF1A (0.56) | HIF1ATSHRTRPV1MAPTFAAH | |
| Glutaral SCHEMBL3241155 | 0.85 | HIF1A (0.67) | HIF1ATSHRTRPV1MAPTFAAH | |
| Glutaral SCHEMBL8620854 | 0.85 | HIF1A (0.67) | HIF1ATSHRTRPV1MAPTFAAH | |
| Glutaral SCHEMBL6775101 | 0.82 | HIF1A (0.62) | HIF1ATSHRTRPV1MAPTFAAH | |
| Glutaral SCHEMBL8434890 | 0.82 | HIF1A (0.62) | HIF1ATSHRTRPV1MAPTFAAH | |
| Sulfurous Acid SCHEMBL8002563 | 0.82 | HIF1A (0.37) | HIF1ATSHRALDH1A1 | |
| Glutaral SCHEMBL9440845 | 0.82 | HIF1A (0.62) | HIF1ATSHRTRPV1MAPTFAAH | |
| Sulfurous Acid SCHEMBL7770699 | 0.82 | HIF1A (0.37) | HIF1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686682-B1 | Dispersion adhesives | CLARIANT GMBH (DE) | 1997-12-03 | — | — | EP | disclosed |
| US-5545684-A | COMPRISES HOMO- OR COPOLYMERIC POLYVINYL ESTERS, POLYMERIC PROTECTIVE COLLOIDS, WATER-SOLUBLE COMPOUNDS WHICH CAN BE COMPLEXED WITH COLLOIDS AND MASKED POLYALDEHYDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | disclosed |
| EP-0686682-A1 | Dispersion adhesives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-13 | — | — | EP | disclosed |