Glutaral

Glutaral

SCHEMBL456725

O=CCCCC=O.O=S([O-])O.O=S([O-])O.[Na+].[Na+]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Glutaral. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.56
TSHR P16473 2/20 0.39
TRPV1 Q8NER1 2/20 0.33
MAPT P10636 1/20 0.33
FAAH O00519 2/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutaral SCHEMBL1359455 1.00 HIF1A (0.56) HIF1ATSHRTRPV1MAPTFAAH
Glutaral SCHEMBL8776299 0.94 HIF1A (0.56) HIF1ATSHRTRPV1MAPTFAAH
Glutaral SCHEMBL9851211 0.94 HIF1A (0.56) HIF1ATSHRTRPV1MAPTFAAH
Sulfurous Acid SCHEMBL8002563 0.88 HIF1A (0.37) HIF1ATSHRALDH1A1
Sulfurous Acid SCHEMBL7770699 0.88 HIF1A (0.37) HIF1ATSHRALDH1A1
Glutaral SCHEMBL7971524 0.86 HIF1A (0.59) HIF1ATSHRTRPV1MAPTFAAH
Sulfurous Acid SCHEMBL10773339 0.85 HIF1A (0.39) HIF1ATSHR
Glutaral SCHEMBL3241155 0.85 HIF1A (0.67) HIF1ATSHRTRPV1MAPTFAAH
Glutaral SCHEMBL8620854 0.85 HIF1A (0.67) HIF1ATSHRTRPV1MAPTFAAH
Glutaral SCHEMBL8434890 0.82 HIF1A (0.62) HIF1ATSHRTRPV1MAPTFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4687731-A STORAGE STABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-08-18 US claimed
EP-0182566-A2 Method for processing lightsensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-05-28 EP claimed
US-4033771-A IRON OR COBALT COMPLEX WITH POLYCARBOXYLIC ACID, THIOSULFATES, CARBONYL BISULFITE ADDUCT EASTMAN KODAK COMPANY (US) 1977-07-05 US claimed
US-20120064464-A1 RADIOGRAPHIC SILVER HALIDE FILMS HAVING INCORPORATED DEVELOPER CARESTREAM HEALTH, INC. 2012-03-15 US disclosed
EP-2411872-A1 RADIOGRAPHIC SILVER HALIDE FILMS HAVING INCORPORATED DEVELOPER Carestream Health, Inc. (US) 2012-02-01 EP disclosed
WO-2010110845-A1 RADIOGRAPHIC SILVER HALIDE FILMS HAVING INCORPORATED DEVELOPER CARESTREAM HEALTH, INC. (US) 2010-09-30 WO disclosed
EP-1240268-B1 DISCOLORATION-FAST DISPERSION ADHESIVES HAVING A PROLONGED POTLIFE CELANESE EMULSIONS GMBH (DE) 2006-12-13 EP disclosed
US-7147996-B2 Method of processing silver halide materials EASTMAN KODAK COMPANY (US) 2006-12-12 US disclosed
US-20060216658-A1 METHOD OF PROCESSING SILVER HALIDE MATERIALS EASTMAN KODAK COMPANY 2006-09-28 US disclosed
WO-2005098421-A2 SENSOR FOR CONTAMINANTS EASTMAN KODAK COMPANY (US) 2005-10-20 WO disclosed
EP-1054295-B1 Developing/fixing monobath and its use for processing low silver black-and-white photographic elements EASTMAN KODAK CO (US) 2005-08-03 EP disclosed
EP-0020742-A4 SHAPED ARTICLES MADE FROM CROSSLINKED ACRYLAMIDE POLYMER COMPOSITIONS. BARD INC C R (US) 1981-05-15 EP disclosed
US-4254008-A FOR OSTOMY SEALS DIAMOND SHAMROCK CORPORATION (US) 1981-03-03 US disclosed
EP-0020742-A1 SHAPED ARTICLES MADE FROM CROSSLINKED ACRYLAMIDE POLYMER COMPOSITIONS. BARD INC C R (US) 1981-01-07 EP disclosed
WO-1980001384-A1 CROSSLINKED ACRYLAMIDE POLYMER COMPOSITIONS AND SHAPED ARTICLES THEREFROM DIAMOND SHAMROCK CORP (US) 1980-07-10 WO disclosed
US-4201585-A POLYOXYETHYLENE COMPOUNDS CARRYING A THIOETHER SIDECHAIN AGFA-GEVAERT, N.V. (BE) 1980-05-06 US disclosed
EP-0001852-A1 Photographic bleach compositions containing bleach-accelerating compounds and their use in a method of processing an image-wise exposed photographic silver halide material AGFA-GEVAERT N.V. (BE) 1979-05-16 EP disclosed
US-4125402-A Method of processing silver dye bleaching materials and preparations suitable for the dye and silver bleaching CIBA-GEIGY AG (CH) 1978-11-14 US disclosed
US-4033771-A IRON OR COBALT COMPLEX WITH POLYCARBOXYLIC ACID, THIOSULFATES, CARBONYL BISULFITE ADDUCT EASTMAN KODAK COMPANY (US) 1977-07-05 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed