Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878097 | 0.90 | KDM4A (0.35) | KDM4AKDM4CPOLBPDK2HRH4 | |
| SCHEMBL877631 | 0.90 | KDM4A (0.35) | KDM4AKDM4CPOLBPDK2HRH4 | |
| SCHEMBL877844 | 0.84 | F10 (0.37) | KDM4AKDM4CPOLBPDK2 | |
| SCHEMBL878580 | 0.83 | ALDH1A1 (0.34) | KDM4AKDM4CPDK2GBA1KDM4E | |
| SCHEMBL877667 | 0.77 | ACACB (0.32) | KDM4AKDM4CPOLBADORA2AADORA1 | |
| SCHEMBL785498 | 0.74 | PDE4A (0.37) | POLBPDK2GBA1PDE4B | |
| SCHEMBL876176 | 0.73 | F10 (0.32) | PDK2PDE4B | |
| SCHEMBL784264 | 0.73 | POLB (0.36) | POLBGBA1KDM4EALDH1A1LMNA | |
| SCHEMBL877421 | 0.73 | CCR5 (0.36) | KDM4AKDM4CPOLBADORA2AADORA1 | |
| SCHEMBL784608 | 0.71 | MEN1 (0.43) | GBA1ALDH1A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | claimed |