Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | LCAT | P04180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877631 | 0.90 | KDM4A (0.35) | KDM4AKDM4CHRH4HRH3POLB | |
| SCHEMBL877666 | 0.90 | KDM4A (0.34) | KDM4AKDM4CHRH4HRH3POLB | |
| SCHEMBL877844 | 0.85 | F10 (0.37) | KDM4AKDM4CPOLBPDK2 | |
| SCHEMBL878580 | 0.84 | ALDH1A1 (0.34) | KDM4AKDM4CPDK2 | |
| SCHEMBL878098 | 0.77 | HRH4 (0.32) | KDM4AKDM4CHRH4HRH3POLB | |
| SCHEMBL877421 | 0.74 | CCR5 (0.36) | KDM4AKDM4CPOLB | |
| SCHEMBL876176 | 0.74 | F10 (0.32) | PDK2 | |
| SCHEMBL784457 | 0.74 | WDR5 (0.36) | HRH4HRH3 | |
| SCHEMBL784801 | 0.72 | POLB (0.36) | HRH4HRH3POLB | |
| SCHEMBL785893 | 0.72 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | claimed |