Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094989 | 0.91 | PTGS2 (0.53) | SQORNPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL8093983 | 0.91 | CNR1 (0.44) | L3MBTL1PTGS2PTGS1CHRNA7CNR1 | |
| SCHEMBL8094551 | 0.90 | CNR1 (0.49) | SQORNPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL8092670 | 0.86 | GLA (0.44) | NPSR1L3MBTL1MEN1KMT2AGPR55 | |
| SCHEMBL8094547 | 0.85 | PTGS2 (0.60) | NPSR1L3MBTL1MEN1KMT2AGPR55 | |
| SCHEMBL8095872 | 0.85 | ALDH1A1 (0.55) | NPSR1L3MBTL1MEN1KMT2APTGS2 | |
| SCHEMBL8095632 | 0.84 | PTGS2 (0.56) | PTGS2PTGS1CNR1CA1CA2 | |
| SCHEMBL8093429 | 0.84 | CNR1 (0.44) | PTGS2PTGS1CNR1CA1CA2 | |
| SCHEMBL8093715 | 0.84 | CNR1 (0.46) | NPSR1L3MBTL1MEN1KMT2AGPR55 | |
| SCHEMBL8092530 | 0.83 | PTGS2 (0.55) | NPSR1L3MBTL1MEN1KMT2AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024584-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |