Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.48 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099937 | 0.90 | CNR1 (0.48) | CNR1CNR2AKT1AKT2SCN9A | |
| SCHEMBL8093312 | 0.89 | CA1 (0.47) | CNR1CNR2AKT1AKT2SCN9A | |
| SCHEMBL8776770 | 0.88 | SCN9A (0.45) | CNR1CNR2AKT1AKT2SCN9A | |
| SCHEMBL8776824 | 0.86 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL8776740 | 0.85 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL8776866 | 0.85 | KDM4E (0.43) | CNR1CNR2AKT1AKT2RORC | |
| SCHEMBL8776720 | 0.83 | PTGS2 (0.47) | CNR1CNR2SCN9ASQOR | |
| SCHEMBL8776778 | 0.81 | CNR1 (0.41) | CNR1CNR2AKT1AKT2RORC | |
| SCHEMBL8776745 | 0.80 | KDM4E (0.46) | CNR1AKT1AKT2 | |
| SCHEMBL8095490 | 0.78 | CNR1 (0.51) | CNR1AKT1AKT2SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | claimed |
| WO-1996024584-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | claimed |